Hello,
I have a Dell Precision T3610, it has a CPU Xeon E5 1650, 32gb ram, 1TB HDD and an AMD Firepro V4900. It runs Windows 10 without any problem.
I use this PC to produce music, video and ilustrations, usually with LMMS, Inkskape, GIMP, Kdenlive, OBS... Since they are all open source...